Principal Investigator
Yiwei Li
李一伟
Dr. Yiwei Li and his laboratory is focused on both the ex vivo assembly and in vivo self-organization of functional tissues/organs from the interface between physics and molecular biology. He studies the mechanoregulation and biophysics in 3D organoid growth using single cell technologies. Their goal is to probe, understand, and engineer the physical properties of 3D multicellular living systems, as well as their crosstalks with gene expression, epigenetic modification, and protein condensation.
Techniques used by the group include organoid culturing, microfluidics, single cell sequencing, mass spectrometry, microrheology. We are also aiming to develop new technology to solve the problems in biophysics and single cell -omics upon the requirement in our researches.
Yiwei Li received a BSc in Biological Science in 2011, and a PhD in Biomedical Engineering in 2016 from Huazhong University of Science and Technology. During his PhD study, he visited the School of Engineering and Applied Science at Harvard University as a Fellow of Applied Physics. He then jointed Department of Mechanical Engineering at MIT from June, 2016 as a Postdoctoral Associate. He also served as an Associate at Harvard University from Nov. 2016 to Oct. 2019. By the end of 2020 and the beginning of 2021, he became a Professor at Huazhong University of Science and Technology.
Professor in Biomedical Engineering
Postdoctoral Associate
Yiran Guo
Yiran Guo received her bachelor’s degree in Bioinformatics from Huazhong University of Science and Technology (HUST, China) in 2012, and received his Ph.D. degree in Biomedical Engineering from HUST in 2021. She is presently a postdoctoral researcher of Biology in HUST. Her major research direction is cell signaling study and cell analysis based on microfluidics.
Co-advised with Prof. Bi-Feng Liu
Zhaolong Gao
Zhaolong Gao received his B.E.and Ph.D degree in control science and engineering from Huazhong University of Science and Technology, Wuhan, China, in 2011 and 2021.
His research interests include machine learning and biological image processing.
He is currently working on applying machine learning to identify the invasive behaviors of cancer cells in both ex vivo 3D molds and clinical samples
Yueming Tian
Yueming Tian received her bachelor’s degree in Biotechnology from Heilongjiang University in 2015, master's degree in Biology from Heilongjiang University and Novosibirsk State University in 2018, and Ph.D degree in Biological science from Novosibirsk State University in 2022.
A researcher who studies ribosome has a passion for biology now and hopes this passion lasts.
Pengjie Li
He is currently working on new methods for quantitatively screening and analyzing phase-separating proteins
Graduate Students
Fukang Qi
Incoming PhD graduate student in Biomedical Engineering
Research interest:
1.Biomechanics;
2. Neurobiology.
Research experience: The effect of nicotine on neural circuits. Use C.elegans as a model organism, research the effect of nicotine on the coordination and interaction of different neural circuits.
Pengjie Li
Co-advised PhD graduate student in Biomedical Engineering
Mengcheng Lei
Co-advised PhD graduate student in Biomedical Engineering
Graduate Students
Fukang Qi
PhD graduate student in Biomedical Engineering
Research interest:
1.Biomechanics;
2. Neurobiology.
Research experience: The effect of nicotine on neural circuits. Use C.elegans as a model organism, research the effect of nicotine on the coordination and interaction of different neural circuits.
Fang Zeng
PhD graduate student in Biomedicine
Zeng fang graduated from the School of Pharmacy at Huazhong University of Science and Technology in 2011 with a Master's degree in Medicine. Following that, she joined Wuhan Union Hospital as a clinical pharmacist. Currently, she is a doctoral student in the Biology and Medicine program at the School of Life Science and Technology, primarily focusing on the research of precise medication for anti-rejection and anti-tumor drugs.
Mengcheng Lei
PhD graduate student in Biomedical Engineering
(Co-advised with Prof. Bi-Feng Liu)
She is working on establishing tumor-adipose assembloids, and study the mechanical reprogramming of both the adipocytes and cancer cells.
Xueqing Ren
PhD graduate student in Biomedical Engineering
(Co-advised with Prof. Bi-Feng Liu)
My hobbies include listening soft music , cooking, and playing badminton.
The goal of my project is to understand the effect of local microenvironment on tumor progression, metastasis, and exosome production.
Peng Ma
PhD graduate student in Biomedical Engineering
(Co-advised with Prof. Bi-Feng Liu)
Peng Ma received his bachelor’s degree in Biomedical Engineering from South-Central Minzu University in 2015, and is currently a Ph.D. candidate at Huazhong University of Science and Technology. He was a visiting student at Stanford University School of Medicine from 2019 to 2020.
His research interest includes paper-based patterns and conductive construct assembled by micro-nano materials and their applications in biomedical sensing.
Zhe Deng
Master graduate student in Biomedical Engineering
Zhe Deng received his bachelor’s degree in Bioinformatics from Huazhong University of Science and Technology in 2021.
His interest is basketball
Jinyun Shi
PhD graduate student in Biomedical Engineering
My work are mainly concerned on the bidirectional regulation of mechanics mediated by Axin phase separation in Wnt/β-catenin signaling,which involves biotechnology such as gene editing,immunofluorescence,stem cell differentiation,etc.
Mingyu Zhang
PhD graduate student in Biomedical Engineering
Mingyu Zhang received his bachelor's degree in biology from Huazhong University of Science and Technology in 2021.
Xiaolu Cai
Master graduate student in Biology
Xiaolu Cai received her bachelor's degree in Chemistry from Zhengzhou University in 2022.
Xinyu Tu
Master graduate student in Biopharmaceutics
Xinyu Tu received his bachelor's degree in Biomedical Engineering from Huazhong University of Science and Technology in 2021.
Yuxiao Shi
Research Associate
Upcoming PhD graduate student
Bachelor's degree in Biotechnology and Master degree in Biomedical Engineering.
With the interests on biomaterials and tissue engineering, he is currently working on synthetic matrix for organoids culture.
Chuncao Deng
PhD graduate student
(Co-advised with Prof. Mingwei Min)
Chuncao completed her Master in June 2018 at Sichuan University. She focused on X chromosomal recombination, which initially inspired her interest in cell biology. In November 2019, she worked as a research assistant in the Bioland Laboratory, and participated in SARS-CoV-2 related projects. In September 2021, she joined the Min Lab to work on cell fate transitions. She became a PhD student in fall 2022.
Jiashuo Li
Master graduate student in Biomedical Engineering
(Co-advised with Prof. Bi-Feng Liu)
Jiashuo Li received his Bachelor's degree in applied Physics from Dalian Maritime University in 2022.
Xinni Guan
PhD graduate student in Biomedical Engineering
(Co-advised with Prof. Hongjie Yao)
Guan Xinni, 22, graduated from Huazhong University of Science and Technology with a bachelor's degree in biomedical engineering in 2023, and is currently a direct doctoral student majoring in biology and medicine at Huazhong University of Science and Technology.
Yi Zou
Master graduate student in Biomedical Engineering
Zou Yi received her bachelor’s degree in Intelligent Medical Engineering from Chongqing University in 2023.
Her hobbies include photography and hiking.
Undergraduate Students
Xiaohe Li
Undergraduate student in College of Life Science and Technology, HUST
Learnng, learning and learning.
As an undergraduate, learning to grow up as quickly as possible in Life Science is the very major job.
Junze Zheng
Undergraduate student in Biomedical Engineering
On such a terrific platform, I will constantly learn new knowledge in various fields, consolidate experimental skills, and lay a good foundation for future advancement.