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Principal Investigator

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Yiwei Li

 

李一伟

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Dr. Yiwei Li and his laboratory is focused on both the ex vivo assembly and in vivo self-organization of functional tissues/organs from the interface between physics and molecular biology. He studies the mechanoregulation and biophysics in 3D organoid growth using single cell technologies. Their goal is to probe, understand, and engineer the physical properties of 3D multicellular living systems, as well as their crosstalks with gene expression, epigenetic modification, and protein condensation.

Techniques used by the group include organoid culturing,  microfluidics, single cell sequencing, mass spectrometry, microrheology. We are also aiming to develop new technology to solve the problems in biophysics and single cell -omics upon the requirement in our researches.

Yiwei Li received a BSc in Biological Science in 2011, and a PhD in Biomedical Engineering in 2016 from Huazhong University of Science and Technology. During his PhD study, he visited the School of Engineering and Applied Science at Harvard University as a Fellow of Applied Physics. He then jointed Department of Mechanical Engineering at MIT from June, 2016 as a Postdoctoral Associate. He also served as an Associate at Harvard University from Nov. 2016 to Oct. 2019. By the end of 2020 and the beginning of 2021, he became a Professor at Huazhong University of Science and Technology.

yiweili@hust.edu.cn

Professor in Biomedical Engineering

Postdoctoral Associate

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Pengjie Li

He is currently working on new methods for quantitatively screening and analyzing phase-separating proteins

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Feng Sun

She graduated with a PhD degree in Wuhan University. She is studying the technology of mechanical mapping and traction froce mapping with organoids.

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Yueming Tian

Yueming Tian received her bachelor’s degree in Biotechnology from Heilongjiang University in 2015,  master's degree in Biology from Heilongjiang University and Novosibirsk State University in 2018, and  Ph.D degree in Biological science from Novosibirsk State University in 2022.
A researcher who studies ribosome has a passion for biology now and hopes this passion lasts.

Graduate Students

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Fukang Qi

Incoming PhD graduate student in Biomedical Engineering

Research interest:

1.Biomechanics;

2. Neurobiology.

Research experience: The effect of nicotine on neural circuits. Use C.elegans as a model organism, research the effect of nicotine on the coordination and interaction of different neural circuits.

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Pengjie Li

Co-advised PhD graduate student in Biomedical Engineering

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Mengcheng Lei

Co-advised PhD graduate student in Biomedical Engineering

Graduate Students

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Fukang Qi

PhD graduate student in Biomedical Engineering

Research interest:

1.Biomechanics;

2. Neurobiology.

Research experience: The effect of nicotine on neural circuits. Use C.elegans as a model organism, research the effect of nicotine on the coordination and interaction of different neural circuits.

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Fang Zeng

PhD graduate student in Biomedicine

Zeng fang graduated from the School of Pharmacy at Huazhong University of Science and Technology in 2011 with a Master's degree in Medicine. Following that, she joined Wuhan Union Hospital as a clinical pharmacist. Currently, she is a doctoral student in the Biology and Medicine program at the School of Life Science and Technology, primarily focusing on the research of precise medication for anti-rejection and anti-tumor drugs.

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Lu Wang

PhD graduate student in Biomedical Engineering

My name is Wang Lu, with a research focus on liver fibrosis mechanism. I enjoy sports, fitness, and watching movies—sports keep me energetic, fitness maintains my health, and watching movies relaxes me and broadens my perspective.
For academic/research exchanges, feel free to contact me at : lulu_wang@hust.edu.cn.

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Yingying Zhang

Master graduate student in Biology and  Biomedicine

Yingying Zhang received her bachelor's degree in Bioinformatics from  Hubei University in 2023

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Weijie Li

PhD graduate student in Biomedical Engineering

Weijie Li received a bachelor's degree in pharmacy in 2009, and a master's degree in medicine in 2014 from Huazhong University of Science and Technology. Following that, she joined Wuhan Tongji Hospital as a clinical pharmacist. Currently, she is a doctoral student in the Biology and Medicine program  focusing on the research of drug delivery systems and tumor targeting therapy.

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Shuting Zhang

PhD graduate student in Biomedical Engineering

(Co-advised with Prof. Bi-Feng Liu)

Shuting Zhang received her bachelor's degree in biopharmaceuticals in 2021 and her master's degree in biomedical engineering in 2024 from Huazhong University of Science and Technology.

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Jinyun Shi

PhD graduate student in Biomedical Engineering

My work are mainly concerned on the bidirectional regulation of mechanics mediated by Axin phase separation in Wnt/β-catenin signaling,which involves biotechnology such as gene editing,immunofluorescence,stem cell differentiation,etc.

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Mingyu Zhang

PhD graduate student in Biomedical Engineering

 

Mingyu Zhang received his bachelor's degree in biology from Huazhong University of Science and Technology in 2021.

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Lantianyu Lei

Master graduate student in Biology

 

Lantianyu Lei received his Bachelor's degree in Materials Science and Engineering from Northwestern Polytechnical University in 2025.

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Xinyu Tu

Master graduate student in Biopharmaceutics

Xinyu Tu received his bachelor's degree in Biomedical Engineering from Huazhong University of Science and Technology in 2021.

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Yuxiao Shi

Research Associate

Upcoming PhD graduate student​

Bachelor's degree in Biotechnology and Master degree in Biomedical Engineering.
With the interests on biomaterials and tissue engineering, he is currently working on synthetic matrix for organoids culture.

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Chuncao Deng

PhD graduate student​

(Co-advised with Prof. Min​gwei Min)

Chuncao completed her Master in June 2018 at Sichuan University. She focused on X chromosomal recombination, which initially inspired her interest in cell biology. In November 2019, she worked as a research assistant in the Bioland Laboratory, and participated in SARS-CoV-2 related projects. In September 2021, she joined the Min Lab to work on cell fate transitions. She became a PhD student in fall 2022.

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Jiashuo Li

Master graduate student in Biomedical Engineering

(Co-advised with Prof. Bi-Feng Liu)

Jiashuo Li received his Bachelor's degree in applied Physics from Dalian Maritime University in 2022.

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Kaiting Zhang

Master graduate student in Biomedical Engineering

Zhang Kaiting received his bachelor's degree in Bio medical Engineering from Hunan University of Technology in 2024.

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Yi Zou

Master graduate student in Biomedical Engineering

Zou Yi received her bachelor’s degree in Intelligent Medical Engineering from Chongqing University in 2023.
Her hobbies include photography and hiking.

Undergraduate Students

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Xiaohe Li

Undergraduate student in College of Life Science and Technology, HUST

Learnng, learning and learning.

 

As an undergraduate, learning to grow up as quickly as possible in Life Science is the very major job.

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Junze Zheng

Undergraduate student in Biomedical Engineering


On such a terrific platform, I will constantly learn new knowledge in various fields, consolidate experimental skills, and lay a good foundation for future advancement.

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Xinhang Peng

Master graduate student in Biomedical Engineering

Peng Xinhang graduated from Hefei University of Technology  with a bachelor's degree in Food Quality and Safety in 2025. 
His hobbies include playing volleyball and basketball.

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Jieqing Wang

Master graduate student in Biomedical Engineering

Jieqing Wang received his bachelor's degree in Biology from Huazhong University of Science and Technology in 2024.

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Jianing Zhou

Master graduate student in Biomedical Engineering

Alumni


Hao Xie         Undergraduate student         PhD student@Tsinghua University


Name         


Position in Lab


Current Position


Shaoxi Zhang         High school trainee         Undergraduate student@Chicago University


Peng Ma         PhD graduate student        Assitant professor@Wuhan Textile University


Zhe Deng         Master graduate student        officer


Yuelai Xin         High school trainee         Undergraduate student@Columbia University


Liu Yang         Visiting Master graduate student         PhD graduate student@Karolinska Institutet


Yiran Guo         Postdoc        Associate Professor @China University of Geosciences


Zhaolong Gao         Postdoc        Director@Start-up of brain-machine interface


Mengcheng Lei         PhD        Scientist@Hubei Chinese Medicine Hospital

Yiwei Lab

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